Exercise Induced Paralysis in Two Young Ghanaian Men

Abstract

We present two cases of young Ghanaian males who presented to the Korle Bu Teaching Hospital between August and September 2013 with a history of exercise induced quadriparesis and diagnosed to have hypokalaemic periodic paralysis. Both patients had had
recurrent paralysis for years without a diagnosis. The condition is part of a heterogeneous group of chanellopathies that affect sodium, potassium, and calcium channels in membrane cells. It has autosomal dominant inheritance with male preponderance, common in Caucasians and Asians and rare in blacks.